Hello,
I noticed that gnome-screenshot becomes unstable and uses the CPU at 100% when you take a screenshot of a specified area.
After some search, I found that it was already discussed in some bugtrackers and a patch is available.
https://bugzilla.redhat.com/show_bug.cgi?id=1353321
https://bugzilla.gnome.org/show_bug.cgi?id=768087#c2
Patch : https://bug768087.bugzilla-attachments.gnome.org/attachment.cgi?id=331215